Randomization tests of disease-marker associations
نویسندگان
چکیده
منابع مشابه
Randomization tests -1- Randomization tests in language typology
Two of the major assumptions that statistical tests make (random sampling, distribution of the data) are not tenable for most typological data. We suggest to use randomization tests, which avoid these assumptions. Randomization is applicable to frequency data, rank data, scalar measurements and ratings, so most typological data can be analyzed with the same tools. We provided a free computer pr...
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Two of the major assumptions that common statistical tests make about random sampling and distribution of the data are not tenable for most typological data. We suggest to use randomization tests, which avoid these assumptions. Randomization is applicable to frequency data, rank data, scalar measurements, and ratings, so most typological data can be analyzed with the same tools. We provided a f...
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15 صفحه اولAnalysis of single-locus tests to detect gene/disease associations.
A goal of association analysis is to determine whether variation in a particular candidate region or gene is associated with liability to complex disease. To evaluate such candidates, ubiquitous Single Nucleotide Polymorphisms (SNPs) are useful. It is critical, however, to select a set of SNPs that are in substantial linkage disequilibrium (LD) with all other polymorphisms in the region. Whethe...
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ژورنال
عنوان ژورنال: Annals of Human Genetics
سال: 1997
ISSN: 0003-4800,1469-1809
DOI: 10.1046/j.1469-1809.1997.6110047.x